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Haga clic pa= ra cambiar el estilo de título
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La biopsia en la patología músculo esquelética=
( 1ª par= te)
Dr Manuel González Gaitano
H.U.C.
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Complicaciones y errores
n1982: Henry J. Mankin: The hazard of the = biopsy:
n20% de biopsias están mal realizadas y conducen a un cambio en el tratamiento correcto
n18% dan complicaciones locales= o generales que pueden conducir a diseminación tumoral.
n5% de las amputaciones se deben a biopsias mal = realizadas.
n1996: Henry J. Mankin: the hazard  of the biopsy revisited , = J. Bone Joint Surg. Am. 78: 656-663
nPrácticamente encuentra los mismos error= es.
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COMPLEJIDAD ACT= UAL
nAntes: Hematoxilina & Eosina
nHoy suma:
nCitoqueratina, Vimentina, Desmin= a
nCitometria de flujo <= /span>
nÍndices de ADN
nInmunohistoquimica=
Mayor tamaño de la muestra
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A QUIEN REALIZAR BIOPSIA?
nDon´t Touch Me  (No necesitan biopsia)
nLesiones fibrosas:
nFibroma no osificante
nDisplasia fibrosa
nExostosis
nEncondroma
nQuiste óseo simple.
nA toda lesión dudosa sin filiar o con cambios = inesperados tanto clínicos como de imagen
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QUIEN DEBE REALIZAR LA BIOPSIA?
nThe hazard of the biopsy
nMusculoskeletal Society:
n18% producen error diagnostico&#= 13;
n9% presentaron complicaciones de= la herida
n10% produjeron un cambio en el tratamiento ideal:
n3% de muertes atribuidas a este = cambio de tratamiento
n
= La realizara la persona que ha dirigido el estudio diagnostico o el preoperatorio y que va a relizar el = tratamiento definitivo del tumor
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